At Antonio's Pizza, we know that variety is the spice of life, which is why we offer more than just pizza. Our freshly baked Calzones are packed with cheesy goodness and a variety of fillings, making them the perfect meal or side. Looking for something light and flavorful? Try our Pesto Pizza, topped with fresh basil and mozzarella. Don’t forget to add a side of our buttery, oven-fresh breadsticks to complete your meal. Whether you're dining in, taking out, or ordering pizza delivery in Port St. Lucie, Antonio’s Pizza always serves up freshness.

Whether you love a classic Margherita pizza or crave the bold flavors of our specialty pizzas, Antonio’s Pizza has something for everyone. Our menu features everything from the fully-loaded Supreme to our signature Mexican Pizza, each made with the freshest ingredients. We pride ourselves on offering the best pizza in Port St. Lucie, available for both pickup and delivery. Each pizza is made to order, ensuring every bite is as fresh and delicious as the last.